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Board Review: Candida
1.
In which patient population undergoing abdominal surgery, should empiric anti-fungal therapy be given?
A) Any abdominal surgery
B) Septic shock
C) Patients with recent abdominal surgery and recurrent gastrointestinal perforations or anastomotic leakages
D) Patients with history of prior antibiotic exposure
None
2.
Which neutropenic patients should receive anti mold drugs for prophylaxis?
A) Anytime a patient develops neutropenia
B) Patients receiving intensive remission induction chemotherapy for acute myeloid leukemia (AML) or myelodysplastic syndrome (MDS) with expected long term neutropenia (> 7 days)
C) Anyone who is undergoing allogeneic hematopoietic stem cell transplantation
D) All of the above
None
3.
Which agents are strongly recommended as first line treatment for Candidemia?
A) Voriconazole
B) Caspofungin
C) Rezafungin
D) Deoxycholate amphotericin B
E). B and C
None
4.
For a candida CNS infection, what is the first line treatment recommended?
A) Echinocandin
B) Intrathecal caspofungin
C) Liposomal amphotericin B and flucytosine
D) Fluconazole
None
5.
When can treatment for candidemia be deescalated to oral treatment?
A) After 5 or more days of echinocandin therapy
B) If the patient is hemodynamically stable
C) Candidemia has cleared and source control has been achieved
D) Susceptibility to oral azole treatment has been confirmed
E) All of the above
None
6.
In which patient population, should therapeutic drug monitoring for antifungal be considered?
A) Premature infants
B) Patients who are critically ill with altered volume of distribution or extracorporal circuits
C) Severe hypoalbuminemia
D) Morbidly obese patients
E) All of the above
None
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