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Board Review: Specific Antibody Deficiency
Questions related to PPID article on
Specific Antibody Deficiency
.
1.
What levels are abnormal in specific antibody deficiency?
A. Quantitative immunoglobulins
B. IgG subsets
C. Response to protein based vaccine
D. Response to conjugate vaccines
E. Response to polysaccharide antigens
None
2.
What are the most common infections seen in SAD?
A. Skin and soft tissue infection
B. Urinary tract infection
C. Upper/lower respiratory infection
D. Intra-abdominal infection
None
3.
What are the most common bacteria leading to invasive infections in SAD?
A. S. pneumoniae
B. H. influenzae
C. Neisseria species
D. All of the above
None
4.
What other diagnoses are associated with polysaccharide vaccine non-response similar to SAD?
A. IgG subclass deficiency
B. CVID
C. Ataxia telangiectasia
D. CLL
E. All of the above
None
5.
Which of the following is considered a normal response to a polysaccharide antigen challenge?
A. Greater than 70% of PPSV titers above 1.3 mcg/mL post vaccination
B. Greater than 50% of PPSV titers above 1.3 mcg/mL post vaccination
C. Two fold increase from baseline titers after vaccination
D. Four fold increase from baseline titers after vaccination
E. A and C
None
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